KU Leuven conducts fundamental and applied research in all academic disciplines with a clear international orientation. In the Times Higher Education ranking KU Leuven is ranked as the 12th European university, while in the Reuters Top 100 of the World’s most innovative institutions, KU Leuven is listed as the first European university. The STADIUS Center for Dynamical Systems, Signal Processing, and Data Analytics (ESAT-STADIUS) is a research division of the Electrical Engineering Department at KU Leuven, with 11 permanent staff members and about 100 PhD & postdoc researchers. Applied and fundamental research is performed in the area of control, system identification, signal processing, machine learning, numerical optimization, and bioinformatics. The bioinformatics team at ESAT-STADIUS is a high-profile bioinformatics team with worldwide visibility. The bioinformatics team at ESAT-STADIUS is recognized for its pioneering work on data fusion for the prioritization of candidate disease-causing genes. The team has been developing innovative machine-learning methods for a wide range of problems in clinical genomics and drug discovery.