Enamine Supervisors

Dmytro Dudenko

Dmytro Dudenko obtained his degree in chemistry (M.Sc.) from Moscow State University (Chemistry Dep.) in 2003.He then joined the group of Prof. Werner Hug at the University of Fribourg (Switzerland) and in 2008 received a PhD degree in Physical Chemistry, with the thesis entitled “Conformationally Flexible Molecules: Determining the Absolute Configuration by Raman Optical Activity”.In 2009 Dmytro has joined the group of Prof. Hans Wolfgang Spiess at the Max Planck Institute for Polymer Research in Mainz (Germany) for a three-year postdoc performing electronic structure simulations of various organic functional materials under supervision of Dr. Daniel Sebastiani and Dr. Michael Ryan Hansen.In 2012 he moved to the University of Warwick, England (UK 850 MHz Solid-State NMR Facility), as a EPSRC Research Fellow and under supervision of Prof. Steven Brown dealt with the modelling of non-covalent interactions in organic solids of bioactive molecules (i.e., nicotinamide, ibuprofen, etc.), aiming at correlating crystal structures theoretically predicted by the AIRSS method (Ab Initio Random Structure Search, https://www.mtg.msm.cam.ac.uk/Codes/AIRSS ) with experimentally resolved data.In March 2015 Dmytro became a Research Fellow sponsored by the Belgian Federal Science Policy Office (BELSPO) in the Laboratory for Chemistry of Novel Materials at the University of Mons.As of May 2018, Dmytro has joined Enamine Ltd and now is in the ChemInformatics group dealing with various computational projects and collaborations in the field of cheminformatics, docking, homology modeling, molecular dynamics simulations, and applying machine learning methods in chemistry.

Ivan S. Kondratov Ivan S. Kondratov graduated from the University of Kyiv (Ukraine) in 2004 with a Master Diploma and got his PhD degree (Candidate of Chemical Sciences) from the Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine. Starting from 2009 he collaborated with Prof. Dr. Günter Haufe (University of Münster, Germany) and was a guest scientist in Münster for several times. He started working for Enamine (Kyiv, Ukraine) at 2011 as synthetic chemist. Since 2017 he is a Head of Medicinal Chemistry department. This department deal with MedChem related projects at Enamine and design of custom libraries and Building Blocks for Drug Disccovery. Ivan Kondratov is an author of 35 original research papers.




Dr. Dmytro S. Radchenko Dr. Dmytro S. Radchenko obtained his PhD degree (Candidate of Sciences Degree) in Organic Chemistry at Kyiv National Taras Shevchenko University in 2011. In 2014-2015 Dmytro joined Anne Ulrich group as a postdoctoral fellow at Karlsruhe Institute of Technology in Germany (Alexander von Humboldt Fellowship Award). He returned back to Enamine in 2015 and has been working there in a Parallel Chemistry department since then. At the moment he is a Head of Parallel Chemistry department. Dmytro’s main scientific interests and area of expertise include the synthesis of conformationally constrained amino acids, diamines, and fluorinated scaffolds for use in drug discovery. As a Head of Parallel chemistry at Enamine he introduced semi-automated parallel synthesis protocols in 96-well plate format employing various liquid handlers. This enabled milligram-scale synthesis to be performed in parallel with greater efficiency compared to the synthesis performed in separate vials. He also focused his efforts on the development of new one-pot protocols for multistep reactions (3 different reagents, 2-3 synthetic steps). This approach allowed greater diversity for the library of screening compounds obtained as a result of a scaffold derivatization.